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Psychosis, Schizophrenia, or Autoimmune Brain Inflammation—New Hope for Some

Psychosis, Schizophrenia, or Autoimmune Brain Inflammation—New Hope for Some

One of the most distressing things a person can go through is a break in their touch with reality—psychosis—whether in themselves or in a loved one. Psychosis is a term for no longer being able to tell what is real from what is not. The various types of psychotic symptoms include:

  • Hallucinations: These are disturbances in perception—perceiving sensory signals that are not coming from the world around us. The most common is auditory hallucination, hearing things without actual sound waves impacting the ear drums, but people can also see, smell, feel, and taste things that are not coming from their environment.
  • Delusions: These are fixed false beliefs—believing things that are objectively contrary to reality; delusional beliefs are not amenable to being changed with evidence and facts.
  • Disorganization of thought and speech: The inability to maintain a clear train of thought; jumping from topic to topic in a nonsensical way.
  • Disorganization of behavior: Gross irrational and chaotic behavior.
  • Catatonia: A severe and abnormal response to people and the environment, such as mutism, echoing sounds repeatedly, copying other’s movements constantly, rigidly holding positions for long periods of time, failure to respond to environmental stimuli, and other symptoms.
  • Severe loss of normal emotional connection: Severe emotional flatness; loss of motivation, disengagement, and isolation.

It has been long understood that psychotic problems are a result of something going wrong with normal brain function. The only exception are shared delusions, when people come to believe something that is false and are resistant to evidence that would expose the falsehood. Shared or group delusions come from social and relational pressures and not brain dysfunction. So, delusions can occur from both brain dysfunction and from social and relational pressures and stresses.

Historically, when a person presented with the various symptoms listed above, they were recognized as having a break from reality and diagnosed with psychosis. If the symptoms persisted over time, they were often diagnosed with schizophrenia.

The exact causes of schizophrenia are still poorly understood, but it is believed to have multiple causes related to brain development, structure, and function. Genetics play a role, increasing vulnerability, but genes do not tell the entire story. Intrauterine environment, toxic exposures, infections, nutritional deficiencies, and environmental stressors all impact the developing brain and can alter normal cellular development, support systems, and connectivity and, thereby, contribute to the development of psychosis later in life. The point is that every person diagnosed with schizophrenia does not have the exact same brain problem; they share a cluster of symptoms that are used to diagnose schizophrenia. But it is currently believed that there are many different underlying contributing factors and brain changes that lead to these symptoms.

 

New Discoveries

What is interesting is that recently, a condition has been discovered that shares the symptoms of schizophrenia and historically would have been diagnosed as schizophrenia but, in fact, is an autoimmune inflammation of the brain. In other words, the body has made antibodies that are acting inappropriately upon certain brain receptors (NMDA) and causing the symptoms of psychosis.

Recently I read an article entitled “Is it psychosis, or an autoimmune encephalitis?” in which the differences between psychosis and this brain inflammatory condition were described. This is important and exciting because the presentations of both these conditions are nearly identical while the underlying causes are quite distinct and the treatments are necessarily different, with the autoimmune condition having a higher likelihood of resolution with appropriate treatment.

The symptoms of the autoimmune brain condition are some combination of the symptoms of psychosis listed above. A person with the autoimmune encephalitis may become disorganized, stop going to classes or work, socially isolate, stop attending to personal hygiene, talk to self, accuse people of being against them, believe others are out to get them, may become catatonic and withdrawn and become mute, or posture in strange ways. Their thoughts may be disorganized; they may be animated or agitated. The point is, there is a marked dysfunctional change from their normal behavior that is recognized by family and friends.

Clues that this may be autoimmune rather than schizophrenia include:

  • Quick onset in less than three months. If such changes have occurred gradually over years in a person who was odd, socially withdrawn, and peculiar since childhood, then it is more likely schizophrenia. But if the person experiences a fairly sudden and acute change in function, then the possibility of autoimmune encephalitis must be considered.
  • Recent history of infection, especially viral infection, prior to the onset of the dysfunction is a red flag warranting workup for autoimmune encephalitis. The underlying problem is that something (in this case, the viral infection) triggers the body’s immune system to make antibodies that attack the NMDA receptors in the brain, thereby causing the psychosis. Thus, a history of fever, malaise, headache, nausea, diarrhea, etc., prior to the onset of symptoms is a signal warranting investigation for an autoimmune cause.
  • Seizures within one year of the onset of the psychotic symptoms. These seizures are usually not the full-body seizures with loss of consciousness, but deep brain seizures that cause moments of confusion, staring off into space, or no symptoms at all and only show electrical slowing on an electroencephalogram (EEG). But seizures of any kind during the first year suggests an autoimmune problem.
  • A recent history of cancer or any abnormality of the ovaries suggests autoimmune encephalitis rather than schizophrenia. The cancer or ovarian problem, in this case, trigger the immune system to make the antibodies that attack the NMDA receptors.
  • A prior history of herpes simplex virus (HSV) encephalitis increases the risk of autoimmune encephalitis and, thus, any person presenting with psychosis who has a history of prior HSV encephalitis should be evaluated for an autoimmune cause of their psychosis. Again, the connection is that the prior herpes viral infection triggered the body to make antibodies that are now attacking the brain.
  • Any symptoms suggestive of a neurological problem, such as a stiff neck, severe headache, neck pain, etc., should raise concerns and justify an autoimmune workup.
  • Presenting with short-term memory loss may indicate an autoimmune cause to the new psychosis.
  • Changes and instability in normal vital signs, such as a racing heart, blood pressure that changes rapidly, and light headedness when standing, are indicators of an underlying autoimmune problem.

If someone you know is suffering with such symptoms, please bring up this possibility to their doctor as autoimmune encephalitis presenting as a psychotic disorder is a newly discovered insight and may not be considered by your loved-one’s doctor. The treatment for autoimmune encephalitis is quite different than that for schizophrenia, with a much higher likelihood of a good outcome.

 

 

 

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My husband is a pastor and I listen to your lesson almost every week. Thank you for helping me in my study life and to help me love the “real” God more.

C. F., NC, USA

 

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I just wanted to personally thank you for your teachings and insight into scripture. I came across your website via my cousin who suggested I look into “Healing the Mind” information. My youngest daughter has been struggling over the last couple of years and it all came to a head this spring. When I started listening to the “Healing the Mind” lectures my own life began to be transformed. I began sharing with all my daughters the concepts you laid out so clearly. I ordered your book and soaked it up. I just want to say “Thank You!” My walk with the Lord has been refreshed and renewed. Your obedience to the Lord is a blessing to so many.

R. K., Anderson, SC, USA

 

Testimony 37

Hearing Dr. Jennings’ presentations in person came at a pivotal moment in my spiritual journey that began about nine months ago, when the fault lines inherent in my belief system began to crack under questions that most reasonable people end up asking about God and His nature. These were questions I couldn’t find answers to, and they shook my faith. I was unable let it go any longer and be satisfied. My Christian experience became distant. I was afraid; the fear in me rose like thorns, pushing me away from Jesus. And then someone heard my questions and introduced me to this ministry, and my life has totally changed.

I can tell you that this new, “present truth” message is far grander and life-changing than when I shifted from being an agnostic and then a nominal Christian. It has radically altered my worldview, because it reveals a God that makes sense. It is a revolution. I believe that Dr. Jennings’ message is the final message that must go to the world. If any message could be called “righteousness by faith,” as abused as that term is by the right and the left, this is that message, because Jennings’ biblical message identifies a God who is different, whose character isn’t an impossible contradiction.

I walk this path now without fear. I see people differently, and the Holy Spirit burns in my heart. Many call Dr. Jennings’ message false and compromising, but it isn’t false, because I’ve seen the fruits within my mind and body. It is not compromising, because in this message is the only road to holiness that makes any sense. No longer do I behold a pagan god who is always angry and suspicious. Instead, I behold a God who is freeing and loving, always working for our good, and giving me every reason to love my enemy even to my own death, just as Jesus pleads with us. God is good.

Anthony L., CA, USA

 

Testimony 26

Your teachings about our heavenly Father have changed my life. Thank you sooooooo very very much! I know He’s doing some serious healing in my heart and life and I look forward to each new day to learn something new about Him and to just hear you speak about Him. Thank you, forever.

Nancy S.

 

Testimony 49

I came into the church at 21, but that is as far as it went. I was so confused about what love is. I couldn’t find it in the bible, because I am not a person that can read between the lines. I have no logic. I have read many, many books; trying to figure out the crux of the matter. They were helpful, but something was still missing. I have become very frustrated to the point of crying out to God, “Where can I go?”  I needed some basics.

I found two books, written by Timothy Jennings, MD, to be very helpful. God showed me that I had lived my whole life in fear. I didn’t even see it. Now, I do. God is so good.  I discovered the “The Remedy”  Dr. Jennings new book, “The God-Shaped Heart!” Oh, I was so excited, I purchased them right away.

I can get rid of most of my books, because “The Remedy” brings the Love of God out so clearly, even I can’t miss it. Now, I want to sit and read my Bible. Wow, what a revelation! It is just simply Awesome! I am so grateful to Jehovah Almighty for hearing my prayer for more understanding! I am so encouraged!

Jackie S.

 

Testimony 32

The message [of Come And Reason Ministries is] for all Christians (and those who may become Christians) and not just Adventists or any other group. It is difficult to imagine why any [anyone] with intellectual and spiritual honesty could find fault with the way you explained the healing substitution concepts and the truth about God’s character, though I know some will reject and criticize. On behalf of those in our group near Tacoma, WA, thank you and your staff for all of the hard work and for sharing the Gospel in this manner. God’s message of healing love will be carried to the whole world and then Jesus will come – He promised it.

Terry U., Tacoma, WA, USA

 

Testimony 65

I have been tuning into your weekly study classes for a while now and wanted express my appreciation for the teachings that ha been a huge blessing in opening up the true message of the word. Viewing scripture under an imposed law theory always, without fail, raised more questions, concerns, and conflicting scripture interpretations that were discouraging at the very least. Looking at scripture through the design law lens has brought more truth to light for me personally and an understanding of our Heavenly Father that places Him “above all others,” where I am now more than thrilled to witness and serve Him.  I “stumbled” across this ministry a year or so ago and would only watch a few minutes at a time. But the more I listened and the longer I paid attention, the more my spiritual eyes were opened to the ever present truths of scripture. The comprehension of the great controversy and it’s origin by the lies perpetrated and perpetuated throughout the Bible on the attack of God’s character and government is truly priceless. Keep up the Good Work! Your servanthood is desperately needed in such a time as this!

Jeff D., Reading, MA, USA

 

Testimony 21

I am absolutly on fire with the message at Come and Reason! I can’t get enough! I’ve read your book, blog, and articles. I’ve listened to your Bible study podcasts, your radio show, and your series – all excellent! It wasn’t until the past couple of years that I have I like I’m becoming “healthy,” with more to share with others than just beasts and commandments! I used to be a Bible worker and preached when the pastors were gone until I had had enough. I didnt realize at the time what the problem was, but i know now… the message wasn’t properly focused. Now my flame is rekindled. All of your little examples are so perfect in explaining something “complicated” and making it easily understood! Now I’m trying to shape it into a life changing evangelistic series! Thank you!

M.T., USA

 

Testimony 31

It was very touching to hear the testimony of your class share how viewing God’s true character has changed their lives. My feelings are the same – there is so much freedom in knowing that God LOVES me – regardless of my… just, REGARDLESS! I’m still blown away by the true gospel, the fact that God is not ready to strike us when we fail. He is not arbitrary. He simply loves us and warns of the natural consequences because He can’t stand to see us suffer. I AM IN LOVE WITH THIS GOD!!!

Ceil V.,  UT, USA

 

Testimony 66

I am incredibly grateful for the transformative impact you’ve had on my life, and words cannot fully express my appreciation. Over the years, I have been an avid listener and follower of C&R and extend my heartfelt thanks for creating the C&R mobile app. It has allowed me to immerse myself in your lessons repeatedly, enabling me to grasp the profound significance about the Character of God, Design Law, the protocols for life, the reasons behind the current chaos, and Christ’s mission to restore everything. They have deeply touched me. Having studied with various churches, I came away with the perception that God is no different from the deities of ancient Greek or Roman mythology—demanding sacrifices and taking pleasure in bloodshed. Thanks to your transformative teachings, I have experienced a profound awakening to the true nature of God and the immense power of His love. It is truly a remarkable and liberating sensation to finally grasp the truth and embrace the empowering nature of God’s laws. My self-perception has become brighter and more infused with love. My journey of growth continues on a daily basis.

Chris P., Lake Mary, FL, USA

 

Testimony 48

I just want to tell you how blessed I have been reading “The Remedy!” It has become a daily part of my devotional relationship with God. In it I have found a God of love and a God that loves me! The bible has come alive for me! It is the first time that I can say that I have felt hope fill my heart as I have read God’s word. This is good news I can share! Thank you, Dr Jennings! Thank you for your heart for others. I can’t put into words how this has set me free! It has strengthened my trust and love for God.

Jason H.

 

Testimony 27

Your teachings about our heavenly Father have changed my life. Thank you sooooooo very very much! I know He’s doing some serious healing in my heart and life and I look forward to each new day to learn something new about Him and to just hear you speak about Him. Thank you, forever.

Nancy S.

 

Testimony 24

I wanted to thank you very much for presenting your understanding of God. I’ve always been troubled by this question: Why did Jesus have to die? Since my conversion I understood that The Father & Jesus are one, I did not have issues with that. But was there not any other way to save us than for Jesus to die? I guess I actually had a question about God – if He is so wise, how come He did not find another way? I did not see the real ‘beauty’  in the cross. Only when you explained the picture in the medical context, Jesus providing medicine for my selfishness, have I started to finally ‘see the light’. Thank you so much. Your seminar, “Healing the Mind,” are absolutely marvelous & have shared them with my family and many other people, including colleagues at work. Thanks, thanks, thanks. May God bless you abundantly in your ministry.

M. W., Australia

 

Testimony 71

When I was 9 years old, I remember setting at our devotional table with a hunger and thirst for God that wanted more, deeper, BETTER. I can remember literally crying and pounding on the table, “I know these teachers didn’t mean to give us error. They taught what THEY had been TAUGHT, but didn’t ANYBODY READ THE BOOK?!?!?” It mattered to me then. It mattered to me as a teenager. It matters now as I teach bible classes. It didn’t have to be so hard as I watched so many give up and lay God’s great plan and gift of salvation aside as being “impossible.” Then, a friend sent me a link to Come And Reason’s website. I grew excited. YES! FINALLY! Then another friend told me to stay away, saying her son had just broken up with a girl because she was involved with Come And Reason and that “Tim Jennings preaches a false gospel.” But, AFTER many years of developing an authentic and, dare I say FUN relationship with Jesus, through the Holy Spirit I see this message has been around a LONG time, since the apostle Paul, Ellen White, Graham Maxwell, Ray Foucher, and yourself (though I admit, you’ve made me back up, rewind and replay the clips, and get out my well-worn Bible on a few things.) I’m so thankful I have found LIGHT during these DARK days. I am not alone.

Vicki DiNitto

Testimony 44

We were given a gift of the DVD set, “God and Your Brain,” and we just finished watching it. The truths in this are so powerful and truly an answer to a prayer. We’re seeing hope where once we thought God wasn’t answering our prayers to be free of certain mindsets. He answered with these DVDs and we are hungry for more. Thank you!

Daniel T., Easley, SC, USA