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Psychosis, Schizophrenia, or Autoimmune Brain Inflammation—New Hope for Some

Psychosis, Schizophrenia, or Autoimmune Brain Inflammation—New Hope for Some

One of the most distressing things a person can go through is a break in their touch with reality—psychosis—whether in themselves or in a loved one. Psychosis is a term for no longer being able to tell what is real from what is not. The various types of psychotic symptoms include:

  • Hallucinations: These are disturbances in perception—perceiving sensory signals that are not coming from the world around us. The most common is auditory hallucination, hearing things without actual sound waves impacting the ear drums, but people can also see, smell, feel, and taste things that are not coming from their environment.
  • Delusions: These are fixed false beliefs—believing things that are objectively contrary to reality; delusional beliefs are not amenable to being changed with evidence and facts.
  • Disorganization of thought and speech: The inability to maintain a clear train of thought; jumping from topic to topic in a nonsensical way.
  • Disorganization of behavior: Gross irrational and chaotic behavior.
  • Catatonia: A severe and abnormal response to people and the environment, such as mutism, echoing sounds repeatedly, copying other’s movements constantly, rigidly holding positions for long periods of time, failure to respond to environmental stimuli, and other symptoms.
  • Severe loss of normal emotional connection: Severe emotional flatness; loss of motivation, disengagement, and isolation.

It has been long understood that psychotic problems are a result of something going wrong with normal brain function. The only exception are shared delusions, when people come to believe something that is false and are resistant to evidence that would expose the falsehood. Shared or group delusions come from social and relational pressures and not brain dysfunction. So, delusions can occur from both brain dysfunction and from social and relational pressures and stresses.

Historically, when a person presented with the various symptoms listed above, they were recognized as having a break from reality and diagnosed with psychosis. If the symptoms persisted over time, they were often diagnosed with schizophrenia.

The exact causes of schizophrenia are still poorly understood, but it is believed to have multiple causes related to brain development, structure, and function. Genetics play a role, increasing vulnerability, but genes do not tell the entire story. Intrauterine environment, toxic exposures, infections, nutritional deficiencies, and environmental stressors all impact the developing brain and can alter normal cellular development, support systems, and connectivity and, thereby, contribute to the development of psychosis later in life. The point is that every person diagnosed with schizophrenia does not have the exact same brain problem; they share a cluster of symptoms that are used to diagnose schizophrenia. But it is currently believed that there are many different underlying contributing factors and brain changes that lead to these symptoms.

 

New Discoveries

What is interesting is that recently, a condition has been discovered that shares the symptoms of schizophrenia and historically would have been diagnosed as schizophrenia but, in fact, is an autoimmune inflammation of the brain. In other words, the body has made antibodies that are acting inappropriately upon certain brain receptors (NMDA) and causing the symptoms of psychosis.

Recently I read an article entitled “Is it psychosis, or an autoimmune encephalitis?” in which the differences between psychosis and this brain inflammatory condition were described. This is important and exciting because the presentations of both these conditions are nearly identical while the underlying causes are quite distinct and the treatments are necessarily different, with the autoimmune condition having a higher likelihood of resolution with appropriate treatment.

The symptoms of the autoimmune brain condition are some combination of the symptoms of psychosis listed above. A person with the autoimmune encephalitis may become disorganized, stop going to classes or work, socially isolate, stop attending to personal hygiene, talk to self, accuse people of being against them, believe others are out to get them, may become catatonic and withdrawn and become mute, or posture in strange ways. Their thoughts may be disorganized; they may be animated or agitated. The point is, there is a marked dysfunctional change from their normal behavior that is recognized by family and friends.

Clues that this may be autoimmune rather than schizophrenia include:

  • Quick onset in less than three months. If such changes have occurred gradually over years in a person who was odd, socially withdrawn, and peculiar since childhood, then it is more likely schizophrenia. But if the person experiences a fairly sudden and acute change in function, then the possibility of autoimmune encephalitis must be considered.
  • Recent history of infection, especially viral infection, prior to the onset of the dysfunction is a red flag warranting workup for autoimmune encephalitis. The underlying problem is that something (in this case, the viral infection) triggers the body’s immune system to make antibodies that attack the NMDA receptors in the brain, thereby causing the psychosis. Thus, a history of fever, malaise, headache, nausea, diarrhea, etc., prior to the onset of symptoms is a signal warranting investigation for an autoimmune cause.
  • Seizures within one year of the onset of the psychotic symptoms. These seizures are usually not the full-body seizures with loss of consciousness, but deep brain seizures that cause moments of confusion, staring off into space, or no symptoms at all and only show electrical slowing on an electroencephalogram (EEG). But seizures of any kind during the first year suggests an autoimmune problem.
  • A recent history of cancer or any abnormality of the ovaries suggests autoimmune encephalitis rather than schizophrenia. The cancer or ovarian problem, in this case, trigger the immune system to make the antibodies that attack the NMDA receptors.
  • A prior history of herpes simplex virus (HSV) encephalitis increases the risk of autoimmune encephalitis and, thus, any person presenting with psychosis who has a history of prior HSV encephalitis should be evaluated for an autoimmune cause of their psychosis. Again, the connection is that the prior herpes viral infection triggered the body to make antibodies that are now attacking the brain.
  • Any symptoms suggestive of a neurological problem, such as a stiff neck, severe headache, neck pain, etc., should raise concerns and justify an autoimmune workup.
  • Presenting with short-term memory loss may indicate an autoimmune cause to the new psychosis.
  • Changes and instability in normal vital signs, such as a racing heart, blood pressure that changes rapidly, and light headedness when standing, are indicators of an underlying autoimmune problem.

If someone you know is suffering with such symptoms, please bring up this possibility to their doctor as autoimmune encephalitis presenting as a psychotic disorder is a newly discovered insight and may not be considered by your loved-one’s doctor. The treatment for autoimmune encephalitis is quite different than that for schizophrenia, with a much higher likelihood of a good outcome.

 

 

 

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Testimony 35

I am so pleased with the response your message is receiving at my church from the middle-aged to the young adults. I have given out 100 copies of the first two seminars and there are more request every week. One of my [class members] came to me after viewing the series, grateful and impressed with how easy the message was retained. He had been a Seventh-day Adventist in fear all his life, and felt like the scales were removed from his eyes after viewing the seminars. I am so impressed by the change I see in members who have received this message, we are in one accord. However, I am sadden by the negative response of the older people. I am verbally attacked anytime I talk about imposed laws, but I believe my mission is to enlightened everyone I can. I watch your Bible Study Class on YouTube every Friday night and I feel like I am apart of the class. All of you are in one accord and I am so blessed to have found you. I pray that all of you continue to spread this message and I am committed to doing my part.

Clara S., Westfield, MA, USA

 

Testimony 41

I have been blessed by your ministry. I have experienced personally, and deeply resonate with, the God of love and the beautiful picture of God’s character that you present. I have seen your seminar series on YouTube, read ‘The Journal of the Watcher’ book, used your mobile app, and also listen/study the bible study lesson with you each week. I concur with many of the thoughts and perspectives that you share. I understand your conclusions on natural laws vs imposed law and the legal/penal substitution (incorrect diagnosis). This makes perfect sense to me.

Bless you for all you do.

Melissa L.

 

Testimony 65

I have been tuning into your weekly study classes for a while now and wanted express my appreciation for the teachings that ha been a huge blessing in opening up the true message of the word. Viewing scripture under an imposed law theory always, without fail, raised more questions, concerns, and conflicting scripture interpretations that were discouraging at the very least. Looking at scripture through the design law lens has brought more truth to light for me personally and an understanding of our Heavenly Father that places Him “above all others,” where I am now more than thrilled to witness and serve Him.  I “stumbled” across this ministry a year or so ago and would only watch a few minutes at a time. But the more I listened and the longer I paid attention, the more my spiritual eyes were opened to the ever present truths of scripture. The comprehension of the great controversy and it’s origin by the lies perpetrated and perpetuated throughout the Bible on the attack of God’s character and government is truly priceless. Keep up the Good Work! Your servanthood is desperately needed in such a time as this!

Jeff D., Reading, MA, USA

 

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Thank you for the ministry you are sharing with us, it is a real blessing to us and especially to my husband and myself! You are encouraging us to think for ourselves and not just to except everything, without thinking it through, with God’s word!

M.K., USA

 

Testimony 36

Thank you and may God continue to bless you as you share with others the intricacies of how we are all “fearfully and wonderfully made”. I must share that you have opened a whole new world to me, and I have found tremendous healing through what you have shared in two of your books, “Could It Be This Simple?” and “The God Shaped Brain.” I praise God for what you shared, what I have learned, and how I have grown and healed! My prayer is that My Precious Jesus will be seen by others in the way I live, act, talk, etc. and they may be encouraged to know He is truly a GREAT God of LOVE, desiring that no one should perish! God Bless you in your continued endeavors to present Him as He really is!

Joleen H. GA, USA

 

Testimony 59

I’m a native Ghanan, but am currently in France for my master’s degree. Prior to this, during my final years at undergraduate studies in Ghana, I was introduced to your ministry and I’ve been immensely blessed by what you share, especially about the Design and Imposed Laws. God richly bless you for that.

One of the first things I did when I arrived in France was to buy all four of your books. They not only helped me, but those I shared them with. I shared the message with an atheist student and I marveled at how God worked mightily in his life. Today this person shares the Love of God with others and debunks theories of who God is not. I want to share what you present in your “Heavenly Sanctuary and Investigative Judgment” pamphlet, because the message brought rest to my soul and I live today as a healthy person.

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Testimony 30

God lead me to your book “The God-Shaped Brain” while I was searching for another book about the brain and then to your interview about your book on HeartWise Ministries [where] I found out about [Come And Reason Ministries]. I’m now devouring the webcasts of your Bible studies. I have been so greatly blessed and I thank God so much for your courage to speak the Truth in love no matter what. Listening to you contrast the two opposing systems (laws) and digging deep to unearth the hidden treasures in the Bible makes me so incredibly happy and I feel very blessed to be part of your Bible Study Group although I live far away. I am just so excited that there is a group of people that is spreading the Truth about the character of God and it saddens me how few realize what our Father in Heaven is really like.

Kessy B., Australia

 

Testimony 31

It was very touching to hear the testimony of your class share how viewing God’s true character has changed their lives. My feelings are the same – there is so much freedom in knowing that God LOVES me – regardless of my… just, REGARDLESS! I’m still blown away by the true gospel, the fact that God is not ready to strike us when we fail. He is not arbitrary. He simply loves us and warns of the natural consequences because He can’t stand to see us suffer. I AM IN LOVE WITH THIS GOD!!!

Ceil V.,  UT, USA

 

Testimony 43

Two years ago I stumbled upon your book, “Could It Be This Simple,” and then found “The God-Shaped Brain” videos on YouTube, your bible study class, and the ‘Come And Reason’ mobile app. I shared your book with a friend and after nine months of showing love, patience, and kindness this person has been changed by the love of God, too. The same love that healed me, I now express to other women in tangible ways, such as to a Baptist woman with high anxiety and childhood trauma. She was extremely happy and relieved when I shared about the so-called “judgment of God” and burning in hell. She had no desire to serve a God that was so harsh. I have repeated the phrase dozens of times to her. “What we believe has power over us, but we have power over what we believe…”

This message that you are sharing has changed my life. I will continue to serve other women and bring this message of God’s healing love to their lives by sharing your books, YouTube videos, and The Remedy Bible app. Keep up the good work. Don’t be discouraged. God is doing a mighty work in and through this ministry!

Jill L., Midwest, USA

 

Testimony 38

Since November 2015, when I started studying Gods word from this God Is Love point of view, my life has been transformed. My troubled marriage of 15 years has been healed and my husband and I are truly happy for the first time in 15 years. Now When I read the word of God I understand it so much better and I can’t help but see Gods love radiating through the pages to humanity. Gods word is living and active and I am blessed beyond measure to be having this amazing experience. God has given me a beautiful understanding of Jn 3:16 that amazes me more and more each day. Thank you again for your ministry.

Helen D., London, England

 

Testimony 29

Thank you for all of your work to correct misconceptions about God’s character. So many people that my husband and I have talked to seem to be against the natural law construct and view it as “errant” and “dangerous.” Having learned more about it through your blogs and lessons, I don’t really understand why they view it that way, except that it means they have to relearn theology they have known for their entire lives. But I’m so excited to relearn this. For the past few years I have been questioning how I could trust a God who punishes arbitrarily and is full of wrath for those who don’t obey His commands. That view made me afraid to “mess up” or “not be good enough,” even within my relationship with God. I really appreciated the point you bring out about God not wanting us to serve Him because we are afraid, but because we love Him.

Melissa H., IN, USA

 

Testimony 64

I’ve been reading the bible and walking with Jesus since I was around 16. I’m 42 now. I’ve mostly been alone in my walk although I went to several churches in different denominations. For the past 3 years God has been showing me His character of agape. It’s been a blessing and changed how I view God and my walk with Jesus. About a year ago I came across the power of love and the principles of design law. These teachings changed how I read scripture and have been such a beautiful blessing. I’m very excited and grateful for these truths. We share these truths of agape, design law and the reality of the principles of the two trees in the garden of Eden with people on Facebook and YouTube. People all over are learning to trust God and His agape design law which makes life possible. Thank you for everything you shared with me. May God continue to bless your ministry and lives.

Bradley M., Hinsdale, NY, USA

 

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R. V. N., South Africa

 

Testimony 39

[This ministry is the] biggest blessing I have ever received! Your DVDs and lessons could not have come at a better time in my life. I have experienced in the past year many difficulties that, if it wasn’t for this wonderful view of God that I have discovered through this ministry, I would not have been able to respond in love and forgiveness. My heart is being transformed everyday by the Calvary-looking God you teach. Hallelujah!! I have tears in my eyes as I write, because my life has taken a complete turn from where I was heading.

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Testimony 58

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